Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p410 | Osteoporosis: treatment | ECTS2016

Can bone turnover markers help to define the duration of bisphosphonate drug holidays?

Statham Louise , Aspray Terry , Abdy Sharon

Background: On cessation of bisphosphonate treatment, while bone mineral density decreases slowly, bone resorptive markers such as C-terminal telopeptide (CTX) increase more quickly and may be useful in monitoring ‘offset’ of action. Our aim was to analyse changes in CTX on stopping long-term bisphosphonate treatment to guide clinical decision-making on the duration of treatment cessation (‘drug holidays’).Subjects and methods: A tota...